Overview
Pharmacokinetic and Metabolism of [14^C] BMS-986177 in Healthy Male Participants
Status:
Completed
Completed
Trial end date:
2019-07-11
2019-07-11
Target enrollment:
0
0
Participant gender:
Male
Male
Summary
This is an ADME study. Human radiolabeled mass balance studies are performed as part of drug development to obtain information about the absorption, distribution, metabolism, and excretion (ADME) of a study treatment. The goals of human ADME studies include the assessment of absorption, distribution, routes and rates of excretion, mass balance, and metabolite profile and identification.Phase:
Phase 1Accepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Bristol-Myers Squibb
Criteria
Inclusion Criteria:- Signed ICF
- Healthy Male
- Body mass index of 18.0 to 32.0 kg/m2, inclusive.
- Agreement to use approved contraception for 94 days post treatment
- Agreement to not donate sperm for 94 days post treatment
Exclusion Criteria:
- Acute or chronic illness
- GI disease current or recent
- History of dizziness or recurring headaches
- Head injury within last 2 years
- GI surgery
- History or evidence of abnormal bleeding